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Donatello® Series 3

Advanced innovation and technology
in tissue processing

AUTOMATIC TISSUE PROCESSOR FOR HISTOLOGICAL SAMPLES
SDSDT9000
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Donatello® Series 3 Redefining Tissue Processing
Advanced innovation and technology in tissue processing
Your unique and unrepeatable sample deserves best-in-class safety.
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Tissue processing is a one-way process where a number of chemicals steps and physical conditions will irreversibly determine the suitable processing of the specimen for the morphological (H&E), IHC and molecular analysis. Diagnostic-therapeutic algorithms for the selection of patients for targeted cancer treatment include immunohistochemical and molecular analysis of histological specimens. That’s why the quality of FFPE (Formalin Fixed Paraffin Embedded) specimens processed is mandatory.

Evolving Diagnostic and Therapeutic Scenario

Clinical care and Patient management

Pathology Diagnosis

Nucleic Acid (DNA, RNA) and protein expression

Target therapies to slow down or inhibit tumor’ growth

Why 3
Discover how Donatello® Series 3 cutting-edge technology redefines tissue processing
DEMONSTRATING THE INTERFERENCE OF TISSUE PROCESSING IN THE EVALUATION OF TISSUE BIOMARKERS: THE CASE OF PD-L1

Ana Caramelo BSc1, António Polónia MD, PhD1,2, João Vale MSc1, Mónica Curado BSc1, Sofia Campelos MD1, Vanessa Nascimento BSc1, Mariana Barros BSc1, Diana Ferreira BSc1, Tânia Pereira BSc1, Beatriz Neves BSc1, Catarina Eloy MD PhD1,2,3.

  • Pathology Laboratory, Institute of Molecular Pathology and Immunology of University of Porto (Ipatimup), Porto, Portugal.
  • Instituto de Investigação e Inovação em Saúde (i3S), Porto, Portugal
  • Faculty of Medicine of University of Porto (FMUP), Porto, Portugal

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All information and data contained in this area, are to be considered private and confidential and is therefore prohibited the dissemination and publication of these data and information to third parties. You shall therefore keep confidential all information and data coming to its attention during the consultation, to keep them with security measures and a degree of care no less than those accorded to its own confidential information. Access to this area requires the full and complete acceptance of the conditions listed; Diapath therefore reserves the right to pursue all offenders under current regulations and to seek compensation for all damages suffered and patiendi.
The Donatello® Series 3 is especially designed to preserve the integrity of proteins and nucleic acids in biological tissue samples suitable for diagnosis and evaluation of biomarkers predictive of therapy response.
Donatello® Series 3,
technology features
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Donatello® Series 3, overview
DEMONSTRATING THE INTERFERENCE OF TISSUE PROCESSING IN THE EVALUATION OF TISSUE BIOMARKERS: THE CASE OF PD-L1
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The results of this study suggest that, analytic conditions less often motive of consideration such as tissue processing, may be major culprits in the lack of consistent results of biomarkers evaluation, such as PD-L1. […]

These observations support others reported in the literature that support the urgent need to standardize tissue processing and to review the basic chemistry associated with the biomarkers evaluation, since it has been proved to fail as a solid quantitative method. […]

This study demonstrates the need to review and standardize the tissue processing in pathology laboratories to cope with the growing needs of precision medicine inherent quantifications and the production of high quality material necessary for computational pathology usage.

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Donatello is safety
for your health.

GREEN SOLUTION - OTTIX

Ottix is Diapath’s patented solution consisting of two reagents replacing the complete alcohol scale and xylene. Through the application of protocols validated and used all over the World for more than ten years, Ottix guarantees better results than traditional reagents, especially when used for processing breast, skin and fatty tissue samples.

ACTIVATED CARBON FILTERS

Donatello® Series 3 has two high performance activated carbon filters for the removal of compound hydrocarbons. The instrument has a suction point, with a dedicated filter, above the processing chamber.

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Flexibility
for your routine

MAXIMUM PRODUCTIVITY

Donatello, thanks to its large processing chamber and its reagent mixing technology, allows to process up to 420 standard biocassettes with a single processing. With the dedicated basket, it is then possible to process up to 112 Slim Mega Cassettes and up to 56 Super Mega Cassettes with a single processing.

FPS - FAST PROCESSING

The FPS (Fast Processing System) is a system that allows the preheating of the reagent in a safe and homogeneous way before its actual use inside the processing chamber. The use of this technology allows for the processing of small biopsies (up to 1 mm thickness) in less than an hour.

Diapath
Italian Iconic Design

Diapath Donatello Series Automatic Tissue Processor is Silver Winner of A’Design Award and Competition in Scientific Instruments, Medical Devices and Research Equipment Design Category.

 

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Remote Assistance Plus

Our solution for overall business continuity. Communicate with Diapath experts. A simple web connection is enough.

  • Speed in solving problems
  • Specialized and tailor-made assistance for you
  • Guaranteed competence
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Optional accessories

FOR THE COMPLETE LIST, CHECK THE TECHNICAL SHEET

SDSPA9066 Basket for Super Mega Cassettes
CRDEA903-IIIPRO UPS
SDSBR0001 Barcode reader cordless for Donatello® Series
CRD-RT01N Router for Remote Assistance
SDSAD0001 Auto dialer 115-230 V
SDSPA9069 Support for pipes
SDXCE9005 ID card USER, RFID-technology-based, 5 pcs
SDSPA9060 Tray for basket
Technical Data /
Regulatory Standards
Maximum cassette capacity
112 slim mega cassettes56 super mega cassettes420 standard cassettes
12 Reagent Tanks
12 tanks of 5 l each
Wax Cylinders
3 cylinders, 4.4-4.7 l each
Maximum Processing Chamber Volume (Spc)
8 l
Reagent Management System (RMS)

Complete control of reagents and activated carbons

Diapath complete range of solution for Anatomic Pathology
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Diapath France Donatello® Series 3 © 2023
Tel: +39 (0)363 986411
Mail: info@diapath.com